Nanoparticles that activate complement in the absence of biological molecules are described. The nanoparticles are shown to specifically target antigen presenting cells in specifically in lymph nodes, without the use of a biological molecule for targeting. These particles are useful vehicles for delivering immunotherapeutics. Surface chemistries and chemical formulations for the nanoparticles are described.
41722294
Alternative title(s) : (de) Nanopartikel für immuntherapie (fr) Nanoparticules pour immunothérapie
TTO:6.0843
Patent number | Country code | Kind code | Date issued |
EP2341897 | EP | B1 | 2021-02-17 |
CA2735318 | CA | C | 2017-10-31 |
JP5806934 | JP | B2 | 2015-11-10 |
CN102202653 | CN | B | 2015-09-02 |
AU2009285628 | AU | B2 | 2015-04-02 |
EP2341897 | EP | A4 | 2013-06-19 |
US8323696 | US | B2 | 2012-12-04 |
JP2012501341 | JP | A | 2012-01-19 |
CN102202653 | CN | A | 2011-09-28 |
EP2341897 | EP | A2 | 2011-07-13 |
WO2010025324 | WO | A3 | 2010-06-24 |
AU2009285628 | AU | A1 | 2010-03-04 |
CA2735318 | CA | A1 | 2010-03-04 |
US2010055189 | US | A1 | 2010-03-04 |
WO2010025324 | WO | A2 | 2010-03-04 |