Process and reactor for the manufacture of powders of inhalable medicaments
The invention relates to an improved process for the production of powders of an inhalable medicament by crystallization from a supersaturated fluid containing said medicament, the method comprising passing along a tubular reactor(a) a segmented flow of that fluid comprised of discrete volumes or(b) a fluid mixture being separated by discrete volumes of a separating fluid which is substantially immiscible with said fluid,characterized in that the crystallization is initiated by application of ultrasound.
33101761
32103884
Alternative title(s) : (de) Verfahren und reaktor zur herstellung von pulvern für inhalative medikamente (fr) Procede de fabrication de poudres pour medicaments pouvant inhales
TTO:6.0379
Patent number | Country code | Kind code | Date issued |
US8496944 | US | B2 | 2013-07-30 |
CA2502502 | CA | C | 2013-06-25 |
JP5172075 | JP | B2 | 2013-03-27 |
AT551993 | AT | T | 2012-04-15 |
EP1585585 | EP | B1 | 2012-04-04 |
US2009068275 | US | A1 | 2009-03-12 |
JP2006504746 | JP | A | 2006-02-09 |
EP1585585 | EP | A2 | 2005-10-19 |
US2004197275 | US | A1 | 2004-10-07 |
WO2004034943 | WO | A3 | 2004-05-27 |
AU2003267433 | AU | A1 | 2004-05-04 |
AU2003267433 | AU | A8 | 2004-05-04 |
CA2502502 | CA | A1 | 2004-04-29 |
WO2004034943 | WO | A2 | 2004-04-29 |