Method for in-vitro monitoring of neuronal disorders and use thereof
The present invention relates to methods and neuronal cellular preparations allowing monitoring intracellular and transcellular molecular events on both short and long timescales in an ex vivo neuronal network of intact post-mitotic neurons. In particular, the invention relates to methods, kits, genetically engineered neuronal cells, preparations and uses thereof allowing the ex vivo monitoring of early neuronal disease- related changes in neuronal network behavior.
44511114
Alternative title(s) : (de) Verfahren zur in-vitro-überwachung von neuronalen erkrankungen sowie anwendung (fr) Procédé pour la surveillance in vitro de troubles neuronaux et son utilisation
TTO:6.0933
| Patent number | Country code | Kind code | Date issued |
EP2591356 | EP | A1 | 2013-05-15 |
US2013109048 | US | A1 | 2013-05-02 |
WO2012004778 | WO | A1 | 2012-01-12 |