Strain-Promoted C-C Bond Cleavages of Cyclobutanes A Molecular Complexity Generating Tool

The catalytic activation of carbon-carbon single bonds is a major challenge in organometallic chemistry, since the lack of prefunctionalization steps opens the way to new, economically and ecologically attractive reaction pathways. Strained ring substrates occupy a privileged role in C-C bond activations as the release of their ring strain facilitates the desired metal insertion. Important progress has been made in the field in the last decade. However, the development of asymmetric versions lags behind. This thesis shows the development of new methodologies for the enantioselective C-C bond activation of cyclobutane derivatives.


Advisor(s):
Cramer, Nicolai
Year:
2015
Publisher:
Lausanne, EPFL
Keywords:
Other identifiers:
urn: urn:nbn:ch:bel-epfl-thesis6531-1
Laboratories:


Note: The status of this file is: EPFL only


 Record created 2015-03-10, last modified 2018-03-17

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