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research article

Hyperpolarized Magnetic Resonance as a Sensitive Detector of Metabolic Function

Comment, Arnaud  
•
Merritt, Matthew E.
2014
Biochemistry

Hyperpolarized magnetic resonance allows for noninvasive measurements of biochemical reactions in vivo. Although this technique provides a unique tool for assaying enzymatic activities in intact organs, the scope of its application is still elusive for the wider scientific community. The purpose of this review is to provide key principles and parameters to guide the researcher interested in adopting this technology to address a biochemical, biomedical, or medical issue. It is presented in the form of a compendium containing the underlying essential physical concepts as well as suggestions to help assess the potential of the technique within the framework of specific research environments. Explicit examples are used to illustrate the power as well as the limitations of hyperpolarized magnetic resonance.

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Type
research article
DOI
10.1021/bi501225t
Web of Science ID

WOS:000345803600001

Author(s)
Comment, Arnaud  
Merritt, Matthew E.
Date Issued

2014

Publisher

Amer Chemical Soc

Published in
Biochemistry
Volume

53

Issue

47

Start page

7333

End page

7357

Editorial or Peer reviewed

REVIEWED

Written at

EPFL

EPFL units
GR-CO  
Available on Infoscience
February 20, 2015
Use this identifier to reference this record
https://infoscience.epfl.ch/handle/20.500.14299/111444
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