Composite hydrogel-loaded alumina membranes for nanofluidic molecular filtration

In this paper a nanofluidic molecular filtration system based on soft alginate hydrogel fillings and a solid-state alumina support membrane is presented. The electrostatically controlled diffusion is characterized by partition coefficient of the hydrogel and the flux through the composite membrane for positively and negatively charged dye molecules. The partition coefficient of negatively charged fluorescein sodium molecules into the gel is 2 orders of magnitude lower in 1 mM KCl solution than that in 1 M KCl solution. The molecular transport properties through the hydrogel loaded alumina membrane are solely dominated by the soft nanoporous hydrogel. Such a composite membrane with alginate hydrogel of only 6 wt% shows a selectivity of 5 for the separation of bovine serum albumin (BSA) and bovine hemoglobin (BHb) in high ionic strength solution of phosphate-buffered saline (PBS). (C) 2014 Elsevier B.V. All rights reserved.


Published in:
Journal of Membrane Science, 477, 1, 151-156
Year:
2015
Publisher:
Elsevier
ISSN:
0376-7388
Keywords:
Laboratories:


Note: The status of this file is: EPFL only


 Record created 2015-01-26, last modified 2018-09-13

n/a:
Download fulltext
PDF

Rate this document:

Rate this document:
1
2
3
 
(Not yet reviewed)