Highly relaxing gadolinium based MRI contrast agents responsive to Mg2+ sensing
2012
Abstract
A Gd complex based on a polyphosphonated pyridyl ligand shows a very high stability in aqueous solution (logK EuL = 25.7), a high relaxivity (8.5 mM -1 s -1 at 25 °C and 20 MHz) and a marked and selective relaxivity enhancement (37%) in the presence of Mg 2+, opening interesting perspectives for the design of cation responsive contrast agents. © 2012 The Royal Society of Chemistry.
Details
Title
Highly relaxing gadolinium based MRI contrast agents responsive to Mg2+ sensing
Author(s)
Abada, Sabah ; Lecointre, Alexandre ; Elhabiri, Mourad ; Esteban-Gomez, David ; Platas-Iglesias, Carlos ; Tallec, Gaylord ; Mazzanti, Marinella ; Charbonniere, Loic J.
Published in
Chemical Communications
Volume
48
Issue
34
Pages
4085-4087
Date
2012
ISSN
1359-7345
Other identifier(s)
View record in Web of Science
Laboratories
GCC
Record Appears in
Scientific production and competences > SB - School of Basic Sciences > ISIC - Institute of Chemical Sciences and Engineering > GCC - Group of Coordination Chemistry
Peer-reviewed publications
Work outside EPFL
Journal Articles
Published
Peer-reviewed publications
Work outside EPFL
Journal Articles
Published
Record creation date
2014-11-07