Real-time protein aggregation monitoring with a Bloch surface wave-based approach

The misfolding and aggregation of amyloid proteins has been associated with incurable diseases such as Alzheimer's or Parkinson's disease. In the specific case of Alzheimer's disease, recent studies have shown that cell toxicity is caused by soluble oligomeric forms of aggregates appearing in the early stages of aggregation, rather than by insoluble fibrils (see Fig.1) [1]. Research on new strategies of diagnosis is imperative to detect the disease prior to the onset of clinical symptoms [2].


Published in:
Biophotonics: Photonic Solutions For Better Health Care Iv, 9129
Presented at:
EUROPT(R)ODE, XII Conference on Optical Chemical Sensors & Biosensors, Athens, Greece, April 13-16, 2014
Year:
2014
Publisher:
Bellingham, Spie-Int Soc Optical Engineering
ISSN:
0277-786X
ISBN:
978-1-62841-077-8
Keywords:
Laboratories:




 Record created 2014-10-09, last modified 2018-03-17

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