A real-time platform for studying the modulatory capacity of epidural stimulation after spinal cord injury
Epidural electrical stimulation (EES) showed promises to improve standing and walking after neurological disorders. To date, EES has been delivered continuously, although time-dependent stimulations would likely be more efficient to activate specific subsets of sensorimotor circuits with the appropriate timing. To address this issue, we developed a real-time stimulation platform that allows to trigger EES during pre-defined phases of the gait cycle in freely walking rats. We leveraged this platform to demonstrate the ability of time-dependent EES to modulate key aspects of locomotor kinematics in rats with complete spinal cord transection. This platform will support the development of personalized stimulation strategies that can be tailored to the need of individual subjects
WOS:000331259200359
2013
978-1-4673-1969-0
New York
4
International IEEE EMBS Conference on Neural Engineering
1449
1452
REVIEWED
Event name | Event place | Event date |
San Diego, CA | NOV 06-08, 2013 | |