Repository logo

Infoscience

  • English
  • French
Log In
Logo EPFL, École polytechnique fédérale de Lausanne

Infoscience

  • English
  • French
Log In
  1. Home
  2. Academic and Research Output
  3. Journal articles
  4. Balgacyclamides, Antiplasmodial Heterocyclic Peptides from Microcystis aeruguinosa EAWAG 251
 
research article

Balgacyclamides, Antiplasmodial Heterocyclic Peptides from Microcystis aeruguinosa EAWAG 251

Portmann, Cyril  
•
Sieber, Simon
•
Wirthensohn, Silvan
Show more
2014
Journal Of Natural Products

The isolation and structural characterization of three new heterocyclic and macrocyclic peptides, balgacyclamides A C, from Microcystis aeruginosa EAWAG 251 are reported. The constitutions were determined by 2D-NMR methods and mass spectrometry, and the configurations were assigned after ozonolysis and hydrolysis by HPLC-MS methods using Marfey's method as well as GC-MS using authentic standards. Balgacyclamides A and B were active against Plasmodium falciparum K1 in the low micromolar range, while displaying low toxicity to rat myoblasts.

  • Details
  • Metrics
Type
research article
DOI
10.1021/np400814w
Web of Science ID

WOS:000333662700018

Author(s)
Portmann, Cyril  
Sieber, Simon
Wirthensohn, Silvan
Blom, Judith F.
Da Silva, Laeticia
Baudat, Emilie
Kaiser, Marcel
Brun, Reto
Gademann, Karl  
Date Issued

2014

Publisher

Amer Chemical Soc

Published in
Journal Of Natural Products
Volume

77

Issue

3

Start page

557

End page

562

Editorial or Peer reviewed

REVIEWED

Written at

EPFL

EPFL units
LSYNC  
Available on Infoscience
May 2, 2014
Use this identifier to reference this record
https://infoscience.epfl.ch/handle/20.500.14299/103150
Logo EPFL, École polytechnique fédérale de Lausanne
  • Contact
  • infoscience@epfl.ch

  • Follow us on Facebook
  • Follow us on Instagram
  • Follow us on LinkedIn
  • Follow us on X
  • Follow us on Youtube
AccessibilityLegal noticePrivacy policyCookie settingsEnd User AgreementGet helpFeedback

Infoscience is a service managed and provided by the Library and IT Services of EPFL. © EPFL, tous droits réservés