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research article

Deep UV generation and direct DNA photo-interaction by harmonic nanoparticles in labelled samples

Staedler, Davide  
•
Magouroux, Thibaud
•
Passemard, Solene  
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2014
Nanoscale

A biophotonics approach based on the nonlinear optical process of second harmonic generation is presented and demonstrated on malignant human cell lines labelled by harmonic nanoparticles. The method enables independent imaging and therapeutic action, selecting each modality by simply tuning the excitation laser wavelength from infrared to visible. In particular, the generation of deep ultraviolet radiation at 270 nm allows direct interaction with nuclear DNA in the absence of photosensitizing molecules.

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Type
research article
DOI
10.1039/c3nr05897b
Web of Science ID

WOS:000332127200056

Author(s)
Staedler, Davide  
Magouroux, Thibaud
Passemard, Solene  
Schwung, Sebastian
Dubled, Marc
Schneiter, Guillaume Stephane
Rytz, Daniel
Gerber-Lemaire, Sandrine  
Bonacina, Luigi
Wolf, Jean-Pierre
Date Issued

2014

Publisher

Royal Society of Chemistry

Published in
Nanoscale
Volume

6

Issue

5

Start page

2929

End page

2936

Editorial or Peer reviewed

REVIEWED

Written at

EPFL

EPFL units
LSPN  
Available on Infoscience
April 2, 2014
Use this identifier to reference this record
https://infoscience.epfl.ch/handle/20.500.14299/102486
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