Quasi-static cyclic tests on reinforced concrete (RC) walls have shown that shear deformations can constitute a significant ratio of the total deformations when the wall is loaded beyond the elastic regime. For slender RC walls that form a stable flexural mechanism the ratio of shear to flexural deformations remains approximately constant over the entire range of imposed displacement ductilities. This paper proposes a method for incorporating shear-flexure interaction effects in equivalent frame models of slender RC walls by coupling the shear force-shear strain relationship to the curvature and axial strain in the member. The suggested methodology is incorporated in a finite element consisting of two interacting spread inelasticity sub-elements representing flexural and shear response, respectively. The element is implemented in the general finite element code IDARC and validated against experimental results of RC cantilever walls. In a second step, it is applied in inelastic static and dynamic analyses of tall wall and wall-frame systems. It is shown that ignoring shear-flexure interaction may lead to erroneous predictions in particular of local ductility and storey drift demands.