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research article
Palladium-Catalyzed Through-Space C(sp3)-H and C(sp2)-H Bond Activation by 1,4-Palladium Migration: Efficient Synthesis of [3,4]- Fused Oxindoles
Palladium two step: Linear anilides were converted into the title compounds in good to excellent yields through a palladium-catalyzed domino carbopalladation/1,4-palladium shift sequence. The C(sp3)-H activation involves a seven-membered palladacycle, and is chemoselective in the presence of competitive C(sp2)H bonds. DMA=N,N-dimethylacetamide, OPiv=pivalate.
Type
research article
Web of Science ID
WOS:000326807900037
Authors
Publication date
2013
Publisher
Published in
Volume
52
Issue
47
Start page
12385
End page
12389
Peer reviewed
REVIEWED
EPFL units
Available on Infoscience
November 13, 2013
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