Azidation of beta-Keto Esters and Silyl Enol Ethers with a Benziodoxole Reagent

The efficient azidation of beta-keto esters and silyl enol ethers using a benziodoxole-derived azide transfer reagent is reported. The azidation of cyclic beta-keto esters could be achieved in up to quantitative yields in the absence of any catalyst. In the case of less reactive linear beta-keto esters and silyl enol ethers, complete conversion and good yields could be obtained by using a zinc catalyst.


Published in:
Organic Letters, 15, 13, 3246-3249
Year:
2013
Publisher:
Washington, American Chemical Society
ISSN:
1523-7060
Laboratories:




 Record created 2013-10-01, last modified 2018-12-03

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