Pattern-Based Sensing of Peptides and Aminoglycosides with a Single Molecular Probe

A coumarin-based molecular probe can be used for the sensing of peptides and aminoglycoside antibiotics. The probe reacts with the primary amine group(s) of the analytes to give a mixture of covalent adducts with distinct colors. Each analyte gives rise to a characteristic UV–vis spectrum. A pattern-based analysis of the spectra allows identifying structurally related analytes. Furthermore, it is possible to obtain information about the quantity and the purity of the analytes.


Published in:
Organic Letters, 15, 3456-3459
Year:
2013
Publisher:
Washington, American Chemical Society
ISSN:
1523-7060
Laboratories:


Note: The status of this file is: EPFL only


 Record created 2013-06-25, last modified 2018-03-18

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