Loading...
research article
Ugi Four-Component Reaction of Alcohols: Stoichiometric and Catalytic Oxidation/MCR Sequences
2013
A new, simple, and efficient procedure for the one-pot Ugi four-component reaction of alcohols instead of aldehydes is described. Using a stoichiometric amount of IBX or only 1-2% of sodium 2-iodobenzenesulfonate in the presence of Oxone, a wide range of primary alcohols were oxidized to the aldehyde that were directly engaged in the Ugi four-component reaction to afford alpha-acetamidoamides in good to excellent yields.
Type
research article
Web of Science ID
WOS:000320298900073
Authors
Publication date
2013
Publisher
Published in
Volume
15
Issue
11
Start page
2854
End page
2857
Peer reviewed
NON-REVIEWED
EPFL units
Available on Infoscience
June 7, 2013
Use this identifier to reference this record