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research article
Surface Modification of Biomaterials for Conjugation with Human Fetal Osteoblasts
2013
Surface functionalization of hydroxyapatite (HA) and β-tricalcium phosphate (TCP) bioceramics with chemical ligands containing a pyrrogallol moiety was developed to improve the adhesion of bone cell precursors to the biomaterials. Fast and biocompatible copper-free click reaction with azido-modified human fetal osteoblasts resulted in improved cell binding to both HA and TCP bioceramics, opening the way for using this methodology in the preparation of cell-engineered bone implants.
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Name
Borcard-CHIMIA-2013.pdf
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Publisher's version
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openaccess
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211.34 KB
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Adobe PDF
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