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research article
Pd(II)-catalyzed intramolecular aminopalladation/direct C–H arylation under aerobic conditions: synthesis of pyrrolo[1,2-a]indoles
2013
Heating a DMA/pivalic acid (v/v = 4/1) solution of diversely substituted 6-(phenylamino)hex-2-ynoates in the presence of a catalytic amount of Pd(OAc)2 under oxygen atmosphere afforded pyrrolo[1,2-a]indoles in moderate to good yields. A domino sequence involving intramolecular aminopalladation followed by C-H activation and reductive elimination was proposed to account for the observed bis-cyclization.
Type
research article
Web of Science ID
WOS:000318457900009
Authors
Publication date
2013
Publisher
Published in
Volume
69
Issue
22
Start page
4415
End page
4420
Peer reviewed
REVIEWED
EPFL units
Available on Infoscience
May 1, 2013
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