000185526 001__ 185526
000185526 005__ 20181203023047.0
000185526 0247_ $$2doi$$a10.1111/jvim.12011
000185526 022__ $$a0891-6640
000185526 02470 $$2ISI$$a000313716200014
000185526 037__ $$aARTICLE
000185526 245__ $$aUse of an Implanted Sacral Nerve Stimulator to Restore Urine Voiding in Chronically Paraplegic Dogs
000185526 260__ $$bWiley-Blackwell$$c2013$$aHoboken
000185526 269__ $$a2013
000185526 300__ $$a7
000185526 336__ $$aJournal Articles
000185526 520__ $$aBackground Loss of urinary control after spinal cord injury increases risk of urinary tract disease and is problematical for owners of affected dogs. Objectives To design, implant, and test a sacral nerve stimulating device for controlling urine voiding in paraplegic dogs. Animals Nine pet dogs with severe thoracolumbar spinal cord injury causing paraplegia, loss of hindquarter sensation, and incontinence for more than 3 months. The procedure was offered prospectively to owners of suitable candidates after the irreversibility of the incontinence had been ascertained. Methods Open label clinical study. Surgically implantable electrode books were designed for insertion and retention of mixed sacral nerves. Sacral nerves were accessed via laminectomy and stimulated to test their ability to elicit detrusor contraction and then inserted into the electrode book, which was attached to a subcutaneously implanted, externally activated receiver. Results In 8/9 dogs, S2 nerves elicited the largest increases in intravesicular pressure with minimum stimulation and were placed in electrode books. Voiding efficiency was >90% in 8 of the 9 implanted dogs. No important detrimental effects of the procedure were observed. Conclusions and Clinical Importance This sacral nerve stimulating implant is a simple and apparently effective neuroprosthetic device that restores urine voiding in paraplegic dogs.
000185526 6531_ $$aBladder
000185526 6531_ $$aIncontinence
000185526 6531_ $$aProsthesis
000185526 6531_ $$aSpinal cord injury
000185526 700__ $$uUniv Bristol, Sch Vet Sci, Bristol BS18 7DU, Avon, England$$aGranger, N.
000185526 700__ $$uUniv Cambridge, Brain Repair Ctr, Cambridge, England$$aChew, D.
000185526 700__ $$uFinetech Med, Welwyn Garden City, Herts, England$$aFairhurst, P.
000185526 700__ $$uUniv Cambridge, Brain Repair Ctr, Cambridge, England$$aFawcett, J. W.
000185526 700__ $$0246296$$g208625$$uEcole Polytech Fed Lausanne, Lausanne, Switzerland$$aLacour, S. P.
000185526 700__ $$uUCL, London, England$$aCraggs, M.
000185526 700__ $$uUCL, London, England$$aMosse, C. A.
000185526 700__ $$uUCL, London, England$$aDonaldson, N.
000185526 700__ $$aJeffery, N. D.
000185526 773__ $$j27$$tJournal Of Veterinary Internal Medicine$$k1$$q99-105
000185526 909C0 $$xU12393$$0252424$$pLSBI
000185526 909CO $$pSTI$$particle$$ooai:infoscience.tind.io:185526
000185526 917Z8 $$x208625
000185526 937__ $$aEPFL-ARTICLE-185526
000185526 973__ $$rREVIEWED$$sPUBLISHED$$aOTHER
000185526 980__ $$aARTICLE