Palmitoylation, pathogens and their host

S-Palmitoylation, the only reversible post-translational lipid modification, confers unique biochemical and functional properties to proteins. Although it has long been known that viral proteins are palmitoylated, recent studies reveal that this modification plays a critical role for pathogens of all kinds and at multiple steps of their life cycle. The present review examines the involvement of S-palmitoylation in infection by viruses, bacteria and parasites and illustrates how pathogens have evolved to manipulate the host palmitoylation machinery.


Published in:
Biochemical Society Transactions, 41, 84-88
Year:
2013
Publisher:
London, Portland Press
ISSN:
0300-5127
Keywords:
Laboratories:




 Record created 2013-03-28, last modified 2018-03-17


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