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research article
Synthesis, characterisation and in vitro anticancer activity of hexanuclear thiolato-bridged arene ruthenium metallaprisms
2013
Hexanuclear thiolato-bridged arene ruthenium metalla-prisms of the general formula [(p-cymene)6Ru6(SR)6(tpt)2]6+ (R=CH2Ph, CH2C6H4-p-tBu, CH2CH2Ph; tpt=2,4,6-tris(4-pyridyl)-1,3,5-triazine), obtained from the dinuclear precursors [(p-cymene)2Ru2(SR)2Cl2], AgCF3SO3 and tpt, have been isolated and fully characterised as triflate salts. The metalla-prisms are highly cytotoxic against human ovarian cancer cells, especially towards the cisplatin-resistant cell line A2780cisR (IC50 <0.25M).
Type
research article
Web of Science ID
WOS:000315142300032
Authors
Furrer, M. A.
•
Garci, A.
•
Denoyelle-Di-Muro, E.
•
Trouillas, P.
•
Giannini, F.
•
Furrer, J.
•
•
•
Süss-Fink, G.
•
Therrien, B.
Publication date
2013
Publisher
Published in
Volume
19
Start page
3198
End page
3203
Peer reviewed
REVIEWED
EPFL units
Available on Infoscience
March 26, 2013
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