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research article
A molecular view of cholesterol-induced condensation in a lipid monolayer
We investigate the interrnolecular interactions in a mixed phospholipid/cholesterol monolayer using the surface-specific technique of vibrational sum frequency generation. This technique allows us to monitor the conformational and orientational order in the phospholipid as the surface pressure and cholesterol content are varied. We find a disproportionally large increase in phospholipid molecular order upon addition of relatively small amounts of cholesterol, a witness to the condensation effect at the molecular level.
Type
research article
Scopus ID
2-s2.0-10944228893
Authors
Publication date
2004
Published in
Volume
108
Issue
50
Start page
19083
End page
19085
Peer reviewed
REVIEWED
EPFL units
Available on Infoscience
February 8, 2013
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