Neuregulins are growth factors that are essential for myogenesis and regulate muscle metabolism. The addition of a recombinant neuregulin-1 isoform, heregulin-beta1(177-244) (Hrg), containing 3 nmol/l of the bioactive epidermal growth factor-like domain, to developing L6E9 myocytes has acute and chronic effects on glucose uptake and enhances myogenesis. Here, we studied the metabolic adaptation of myocytes to chronic treatments with Hrg.
Type
research article
Authors
Cantó, Carles
•
Pich, Sara
•
Paz, José C.
•
Sanches, Rosario
•
Martínez, Vicente
•
Orpinell, Meritxell
•
Palacín, Manuel
•
Zorzano, Antonio
•
Gumà, Anna
Publication date
2007
Published in
Volume
56
Issue
9
Start page
2185
End page
93
Peer reviewed
REVIEWED
EPFL units
Available on Infoscience
November 8, 2012
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