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research article
Visualizing Biochemical Activities in Living Cells through Chemistry
2011
The development of molecular probes to visualize cellular processes is an important challenge in chemical biology. One possibility to create such cellular indicators is based on the selective labeling of proteins with synthetic probes in living cells. Over the last years, our laboratory has developed different labeling approaches for monitoring protein activity and for localizing synthetic probes inside living cells. In this article, we review two of these labeling approaches, the SNAP-tag and CLIP-tag technologies, and their use for studying cellular processes.
Type
research article
Web of Science ID
WOS:000298362000010
Authors
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Umezawa, Keitaro
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Publication date
2011
Published in
Volume
65
Start page
868
End page
871
Peer reviewed
REVIEWED
EPFL units
Available on Infoscience
June 25, 2012
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