Nanomechanics of Streptavidin Hubs for Molecular Materials

A new strategy is reported for creating protein-based nanomaterials by genetically fusing large polypeptides to monomeric streptavidin and exploiting the propensity of streptavidin monomers(SM) to self-assemble into stable tetramers. We have characterized the mechanical properties of streptavidin-linked structures and measured, for the first time, the mechanical strength of streptavidin tetramers themselves. Using streptavidin tetramers as molecular hubs offers a unique opportunity to create a variety of well-defined, self-assembled protein-based (nano) materials with unusual mechanical properties.


Publié dans:
Advanced Materials, 23, 5684-+
Année
2011
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 Notice créée le 2012-06-12, modifiée le 2019-12-05


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