In vivo 13C NMR spectroscopy and metabolic modeling in the brain: a practical perspective

In vivo 13C NMR spectroscopy has the unique capability to measure metabolic fluxes noninvasively in the brain. Quantitative measurements of metabolic fluxes require analysis of the 13C labeling time courses obtained experimentally with a metabolic model. The present work reviews the ingredients necessary for a dynamic metabolic modeling study, with particular emphasis on practical issues. © 2006 Elsevier Inc. All rights reserved.


Published in:
Magnetic Resonance Imaging, 24, 4, 527-539
Year:
2006
ISSN:
0730725X
Laboratories:




 Record created 2012-05-26, last modified 2018-09-13

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