The journey of resveratrol from yeast to human
The natural polyphenolic compound resveratrol was first discovered in the 1940s. In the recent years, this compound received renewed interest as several findings implicated resveratrol as a potent SIRT1 activator capable of mimicking the effects of calorie restriction, and regulating longevity in lower organisms. Given the worldwide increase in age-related metabolic diseases the beneficial effects of resveratrol on metabolism and healthy aging in humans are currently a topic of intense investigation.
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Keywords: Resveratrol ; Sirt1 ; sirtuins ; calorie restriction ; aging ; metabolic diseases ; Activated Protein-Kinase ; Moderate Wine Consumption ; Life-Span ; Trans-Resveratrol ; Caloric Restriction ; Liquid-Chromatography ; Insulin Sensitivity ; Healthy-Volunteers ; Sirt1 Activation ; Clinical-Trials
Record created on 2012-05-18, modified on 2016-08-09