Loading...
research article
Short-course therapy with daily rifapentine in a murine model of latent tuberculosis infection
Regimens recommended to treat latent tuberculosis infection (LTBI) are 3 to 9 months long. A 2-month rifampin+pyrazinamide regimen is no longer recommended. Shorter regimens are highly desirable. Because substituting rifapentine for rifampin in the standard regimen for active tuberculosis halves the treatment duration needed to prevent relapse in mice, we hypothesized daily rifapentine-based regimens could shorten LTBI treatment to 2 months or less.
Type
research article
Authors
Publication date
2009
Volume
180
Issue
11
Start page
1151
End page
7
Peer reviewed
NON-REVIEWED
EPFL units
Available on Infoscience
April 27, 2012
Use this identifier to reference this record