Thalamic control of cortical states

We investigated the impact of thalamus on ongoing cortical activity in the awake, behaving mouse. We demonstrate that the desynchronized cortical state during active behavior is driven by a centrally generated increase in thalamic action potential firing, which can also be mimicked by optogenetic stimulation of the thalamus. The thalamus therefore is key in controlling cortical states.


Published in:
Nature Neuroscience, 15, 3, 370-372
Year:
2012
Publisher:
Nature Publishing Group
ISSN:
1097-6256
Keywords:
Laboratories:




 Record created 2012-03-29, last modified 2018-09-13


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