Synthesis of new oxathiazinane dioxides and their in vitro cancer cell growth inhibitory activity
Borcard, Francoise; Baud, Matthias; Bello, Claudia; Dal Bello, Giovanna; Grossi, Francesco; Pronzato, Paolo; Cea, Michele; Nencioni, Alessio; Vogel, Pierre
2010

Abstract

New oxathiazinane dioxides have been derived from D- and L-serine and tested for their in vitro cell growth inhibitory activity toward SKBR3 breast cancer cells. (5R)-5-(4-(4'-Bromomethyl)phenyl)benzyloxymethyl-[1,3,4]-oxathiazinane- 3,3-dioxide showed a cytotoxicity of IC50 approximate to 10 mu M. (C) 2009 Elsevier Ltd. All rights reserved.

Details

Title Synthesis of new oxathiazinane dioxides and their in vitro cancer cell growth inhibitory activity
Author(s) Borcard, Francoise ; Baud, Matthias ; Bello, Claudia ; Dal Bello, Giovanna ; Grossi, Francesco ; Pronzato, Paolo ; Cea, Michele ; Nencioni, Alessio ; Vogel, Pierre
Published in Bioorganic & Medicinal Chemistry Letters
Volume 20
Pages 5353-5356
Date 2010
Keywords
DOI https://doi.org/10.1016/j.bmcl.2009.09.019
Other identifier(s) View record in Web of Science
Laboratories LGSA
Record Appears in Scientific production and competences > SB - School of Basic Sciences > SB Archives > LGSA - Laboratory of Glycochemistry and Asymmetric Synthesis
Peer-reviewed publications
Work produced at EPFL
Journal Articles
Published
Record creation date 2011-12-16

Actions