Approximation of event probabilities in noisy cellular processes
Molecular noise, which arises from the randomness of the discrete events in the cell, significantly influences fundamental biological processes. Discrete-state continuous-time stochastic models (CTMC) can be used to describe such effects, but the calculation of the probabilities of certain events is computationally expensive.
Keywords: Chemical master equation ; Gillespie simulation ; Markov chain ; Infinite-state model ; Gene-Expression ; Stochastic Simulation ; Escherichia-Coli ; Networks ; Systems ; Robustness ; Kinetics ; Rhythms ; Fate
Record created on 2011-12-16, modified on 2016-08-09