Transcriptional signatures of regulatory and toxic responses to benzo-[a]-pyrene exposure

Background: Small molecule ligands often have multiple effects on the transcriptional program of a cell: they trigger a receptor specific response and additional, indirect responses ("side effects"). Distinguishing those responses is important for understanding side effects of drugs and for elucidating molecular mechanisms of toxic chemicals.


Published in:
BMC Genomics, 12, 1, 502
Year:
2011
Publisher:
BioMed Central
ISSN:
1471-2164
Keywords:
Laboratories:




 Record created 2011-12-12, last modified 2018-03-17


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