Ruthenium-Catalyzed Sequential Enyne Cross-Metathesis/ATRA Reactions

Sequential enyne cross-metathesis reactions of arylalkynes with ethylene followed by atom transfer radical addition (ATRA) with ethyl dichloroacetate or dichloroacetonitrile provide 1,5-dichloropent-2-ene derivatives. The second-generation Grubbs alkylidene complex [RuCl2(=CHPh)(PCy3)(NHC)] [NHC = 1,3-bis(2,4,6-trimethylphenyl)-2-imidazolidinylidene] is used as the catalyst precursor for both reactions. Preliminary results show that the reaction products can be converted into vinylcyclopropanes by dechlorination with magnesium or manganese.


Published in:
European Journal of Organic Chemistry, 93-98
Year:
2012
Publisher:
Wiley-Blackwell
ISSN:
1434-193X
Keywords:
Laboratories:


Note: The status of this file is: EPFL only


 Record created 2011-11-18, last modified 2018-03-17

n/a:
Download fulltext
PDF

Rate this document:

Rate this document:
1
2
3
 
(Not yet reviewed)