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research article
syn-Selective Rhodium(I)-Catalyzed Allylations of Ketimines Proceeding through a Directed C-H Activation/Allene Addition Sequence
Rhodium(I)-catalyzed C-H functionalization of aryl ketimines and subsequent carborhodation of a terminal allene resulted in the formation of allyl rhodium intermediates, which underwent allylation of the imine to give cyclized products, e.g., I, with high regioselectivity and diastereoselectivity. Preliminary attempts to develop an enantioselective variant were also successful.
Type
research article
Authors
Publication date
2010
Publisher
Published in
Volume
49
Start page
8181
End page
8184
Note
CAPLUS AN 2010:1326885(Journal)
Peer reviewed
REVIEWED
Written at
OTHER
EPFL units
Available on Infoscience
August 17, 2011
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