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research article
Cinchona Alkaloid-Amides Catalyzed Enantioselective Formal [2+2] Cycloadditions of Allenoates and Imines: Enantioselective Synthesis of 2,4-Substituted Azetidines
Mix and go. The quinidine-amide (1)-catalyzed [2+2] cycloaddition between N-sulfonylimines (2) and alkyl 2,3-butadienoate (3) afforded the (R)-azetidines 4 in excellent yields and enantioselectivities. The (S)-enantiomer was obtained when a quinine-amide catalyst, the pseudoenantiomer of (1) was used.
Type
research article
Web of Science ID
WOS:000291953200023
Authors
Publication date
2011
Publisher
Volume
50
Issue
23
Start page
5356
End page
5360
Peer reviewed
REVIEWED
EPFL units
Available on Infoscience
May 31, 2011
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