Synthesis of Hydroxylated 3,4-Dihydropyridine-2-ones from Intramolecular Nucleophilic Addition Reaction of Oxirane-containing Tertiary Enamides

Catalyzed by p-toluenesulfonic acid in dry acetonitrile, oxirane-containing tertiary enamides underwent efficient cyclization via intramolecular addition to produce 3-hydroxy-3,4-dihydropyridin-2(1H)-one derivatives in moderate to good yields.


Published in:
Synlett, 7, 927-930
Year:
2011
Publisher:
Georg Thieme Verlag
ISSN:
0936-5214
Keywords:
Laboratories:




 Record created 2011-04-30, last modified 2018-03-17


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