Access to Macrocycles with an endo Aryl ether and an endo Aryl-Aryl Bond, Development and Application

Macrocyclization methodologies allowing access to macrocycles having an endo ary ether and an endo ary-aryl bond, especially those based on an intramolecular SNAr reaction and the Suzuki-Miyaura reaction, were summarized. Total synthesis of complestatin, a bis-macrocyclic natural product, featuring these two technologies was presented.


Published in:
Chimia, 65, 3, 168-174
Year:
2011
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Note: PRIVATE


 Record created 2011-04-04, last modified 2018-09-13

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