Constitutionally selective amplification of multicomponent 84-membered macrocyclic hosts for (−)-cytidine•H+

Mixtures of dipeptide monomers create stereochemically and constitutionally complex dynamic libraries of potential receptors. When (−)-cytidine was utilized as guest an 84-membered cyclic host was amplified (70–175 fold) from a nearly undetectable initial concentration. Only the specified diastereomeric combination of the two chiral building blocks yielded a dynamic library from which the macrocyclic receptor could be amplified.


Published in:
Chemical Science, 2, 744-747
Year:
2011
Keywords:
Laboratories:


Note: The status of this file is: EPFL only


 Record created 2011-03-10, last modified 2018-01-28

External link:
Download fulltext
Fulltext
Rate this document:

Rate this document:
1
2
3
 
(Not yet reviewed)