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research article
Chiral Phosphoric Acid-Catalyzed Enantioselective Transfer Hydrogenation of ortho-Hydroxyaryl Alkyl N-H Ketimines
2010
The first enantioselective chiral phosphoric acid-catalyzed transfer hydrogenation of unprotected ortho-hydroxyaryl alkyl N-H ketimines using Hantszch di-tert-butyl ester as a reductant is reported. A variety of ortho-hydroxybenzylamines were obtained in good to excellent yields and enantiomeric excesses.
Type
research article
Authors
Publication date
2010
Publisher
Published in
Volume
12
Issue
20
Start page
4705
End page
4707
Peer reviewed
REVIEWED
EPFL units
Available on Infoscience
February 17, 2011
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