Photodynamic Therapy Selectively Enhances Liposomal Doxorubicin Uptake in Sarcoma Tumors to Rodent Lungs
2010
Abstract
Background: In specific conditions, photodynamic therapy (PDT) can enhance the distribution of macromolecules across the endothelial barrier in solid tumors. It was recently postulated that tumor neovessels were more responsive to PDT than the normal vasculature. We hypothesized that Visudyne (R)-mediated PDT could selectively increase liposomal doxorubicin (Liporubicin (TM)) uptake in sarcoma tumors to rodent lungs while sparing the normal surrounding tissue.
Details
Title
Photodynamic Therapy Selectively Enhances Liposomal Doxorubicin Uptake in Sarcoma Tumors to Rodent Lungs
Author(s)
Cheng, Cai ; Debefve, Elodie ; Haouala, Amina ; Andrejevic-Blant, Snezana ; Krueger, Thorsten ; Ballini, Jean-Pierre ; Peters, Solange ; Decosterd, Laurent ; van den Bergh, Hubert ; Wagnieres, Georges ; Perentes, Jean Y. ; Ris, Hans-Beat
Published in
Lasers In Surgery And Medicine
Volume
42
Pages
391-399
Date
2010
Publisher
Wiley-Blackwell
ISSN
0196-8092
Keywords
Other identifier(s)
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Record Appears in
Scientific production and competences > SB - School of Basic Sciences > ISIC - Institute of Chemical Sciences and Engineering > GPM - Medical photonics group
Scientific production and competences > STI - School of Engineering > STI Archives > GR-VDB - Van den Bergh Group
Scientific production and competences > SB - School of Basic Sciences > SB Archives > GR-VDB - Van den Bergh Group
Peer-reviewed publications
Work produced at EPFL
Journal Articles
Published
Scientific production and competences > STI - School of Engineering > STI Archives > GR-VDB - Van den Bergh Group
Scientific production and competences > SB - School of Basic Sciences > SB Archives > GR-VDB - Van den Bergh Group
Peer-reviewed publications
Work produced at EPFL
Journal Articles
Published
Record creation date
2011-01-27