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research article
Photodynamic Therapy Selectively Enhances Liposomal Doxorubicin Uptake in Sarcoma Tumors to Rodent Lungs
Background: In specific conditions, photodynamic therapy (PDT) can enhance the distribution of macromolecules across the endothelial barrier in solid tumors. It was recently postulated that tumor neovessels were more responsive to PDT than the normal vasculature. We hypothesized that Visudyne (R)-mediated PDT could selectively increase liposomal doxorubicin (Liporubicin (TM)) uptake in sarcoma tumors to rodent lungs while sparing the normal surrounding tissue.
Type
research article
Web of Science ID
WOS:000279334500006
Authors
Cheng, Cai
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Haouala, Amina
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Andrejevic-Blant, Snezana
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Krueger, Thorsten
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Ballini, Jean-Pierre
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Peters, Solange
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Decosterd, Laurent
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Publication date
2010
Publisher
Published in
Volume
42
Start page
391
End page
399
Peer reviewed
REVIEWED
Available on Infoscience
January 27, 2011
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