Discovery, structure, and anticancer activity of an iridium complex of diselenobenzoquinone

Caught in the act: The first stable η4-diseleno-p-benzoquinone complex, [Cp*lr(η4-C6H4Se2)], has been isolated. The X-ray structure confirms the coordination of the elusive diselenobenzoquinone intermediate. The anticancer activity of this complex was compared to related oxygen and sulfur analogs; only the diseleno complex was cytotoxic, having a comparable activity to cisplatin.


Published in:
Angewandte Chemie, International Edition , 49, 41, 7530-7533
Year:
2010
Keywords:
Laboratories:




 Record created 2010-12-14, last modified 2018-03-17


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