Discovery, structure, and anticancer activity of an iridium complex of diselenobenzoquinone
Caught in the act: The first stable η4-diseleno-p-benzoquinone complex, [Cp*lr(η4-C6H4Se2)], has been isolated. The X-ray structure confirms the coordination of the elusive diselenobenzoquinone intermediate. The anticancer activity of this complex was compared to related oxygen and sulfur analogs; only the diseleno complex was cytotoxic, having a comparable activity to cisplatin.
Keywords: coordination modes ; iridium ; quinones ; reactive intermediates ; selenium ; Quinone Methide Complexes ; Crystal-Structure ; Coenzyme-Q ; Reactivity ; Benzoquinones ; Assemblies ; Selenium ; Linkers ; Span
Record created on 2010-12-14, modified on 2016-08-09