Discovery, structure, and anticancer activity of an iridium complex of diselenobenzoquinone
Caught in the act: The first stable η4-diseleno-p-benzoquinone complex, [Cp*lr(η4-C6H4Se2)], has been isolated. The X-ray structure confirms the coordination of the elusive diselenobenzoquinone intermediate. The anticancer activity of this complex was compared to related oxygen and sulfur analogs; only the diseleno complex was cytotoxic, having a comparable activity to cisplatin.
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Amouri, H., Moussa, J., Renfrew, A. K., Dyson, P. J., Rager, M. N., & Chamoreau, L.-M. (2010). Discovery, structure, and anticancer activity of an iridium complex of diselenobenzoquinone. Angewandte Chemie International Edition, 49(41), 7530–7533. https://doi.org/10.1002/anie.201002532
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WOS:000283391800028
2010
49
41
7530
7533
REVIEWED
EPFL