Repository logo

Infoscience

  • English
  • French
Log In
Logo EPFL, École polytechnique fédérale de Lausanne

Infoscience

  • English
  • French
Log In
  1. Home
  2. Academic and Research Output
  3. Journal articles
  4. Wound repair and regeneration
 
review article

Wound repair and regeneration

Gurtner, Geoffrey C.
•
Werner, Sabine
•
Barrandon, Yann  
Show more
2008
Nature

The repair of wounds is one of the most complex biological processes that occur during human life. After an injury, multiple biological pathways immediately become activated and are synchronized to respond. In human adults, the wound repair process commonly leads to a non-functioning mass of fibrotic tissue known as a scar. By contrast, early in gestation, injured fetal tissues can be completely recreated, without fibrosis, in a process resembling regeneration. Some organisms, however, retain the ability to regenerate tissue throughout adult life. Knowledge gained from studying such organisms might help to unlock latent regenerative pathways in humans, which would change medical practice as much as the introduction of antibiotics did in the twentieth century.

  • Details
  • Metrics
Type
review article
DOI
10.1038/nature07039
Web of Science ID

WOS:000255868400038

Author(s)
Gurtner, Geoffrey C.
•
Werner, Sabine
•
Barrandon, Yann  
•
Longaker, Michael T.
Date Issued

2008

Published in
Nature
Volume

453

Issue

7193

Start page

314

End page

321

Subjects

Multipotent Stem-Cells

•

Marrow-Derived Cells

•

Growth-Factor-Beta

•

Hair-Follicles

•

Limb-Regeneration

•

Tissue-Repair

•

Transcriptional Control

•

Keratinocyte Migration

•

Inflammatory Cells

•

Epithelial Repair

Editorial or Peer reviewed

REVIEWED

Written at

EPFL

EPFL units
LDCS  
Available on Infoscience
November 30, 2010
Use this identifier to reference this record
https://infoscience.epfl.ch/handle/20.500.14299/61398
Logo EPFL, École polytechnique fédérale de Lausanne
  • Contact
  • infoscience@epfl.ch

  • Follow us on Facebook
  • Follow us on Instagram
  • Follow us on LinkedIn
  • Follow us on X
  • Follow us on Youtube
AccessibilityLegal noticePrivacy policyCookie settingsEnd User AgreementGet helpFeedback

Infoscience is a service managed and provided by the Library and IT Services of EPFL. © EPFL, tous droits réservés