Enhanced and Enduring Protection against Tuberculosis by Recombinant BCG-Ag85C and Its Association with Modulation of Cytokine Profile in Lung
Jain, Ruchi; Dey, Bappaditya; Dhar, Neeraj; Rao, Vivek; Singh, Ramandeep; Gupta, Umesh D.; Katoch, V. M.; Ramanathan, V. D.; Tyagi, Anil K.
2008

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Abstract

Background: The variable efficacy (0-80%) of Mycobacterium bovis Bacille Calmette Gurein (BCG) vaccine against adult tuberculosis (TB) necessitates development of alternative vaccine candidates. Development of recombinant BCG (rBCG) over-expressing promising immunodominant antigens of M. tuberculosis represents one of the potential approaches for the development of vaccines against TB.

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Title Enhanced and Enduring Protection against Tuberculosis by Recombinant BCG-Ag85C and Its Association with Modulation of Cytokine Profile in Lung
Author(s) Jain, Ruchi ; Dey, Bappaditya ; Dhar, Neeraj ; Rao, Vivek ; Singh, Ramandeep ; Gupta, Umesh D. ; Katoch, V. M. ; Ramanathan, V. D. ; Tyagi, Anil K.
Published in Plos One
Volume 3
Issue 12
Pages e3869
Date 2008
Publisher Public Library of Science
ISSN 1932-6203
DOI https://doi.org/10.1371/journal.pone.0003869
Other identifier(s) View record in Web of Science
Laboratories SV
Record Appears in Scientific production and competences > Unattributed publications > SV - SV - Unattributed publications
Scientific production and competences > SV - School of Life Sciences > SV - Unattributed publications
Peer-reviewed publications
Work produced at EPFL
Journal Articles
Published
Record creation date 2010-11-30

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