Photocatalytic lithography (PCL) is an inexpensive, fast, and robust method of oxidizing surface chemical moieties to produce patterned substrates. This technique has utility in basic biological research as well as various biochip applications. We report on porphyrin-based PCL for patterning poly(propylene sulfide) block copolymer films on gold substrates on the micrometer and submicrometer scales. We confirm chemical patterning with imaging ToF-SIMS and low-voltage SEM. Biomolecular patterning on micrometer and submicrometer scales is demonstrated with proteins, protein-linked beads. and fluorescently labeled proteins.
Type
research article
Web of Science ID
WOS:000262431100082
Authors
Bearinger, Jane P.
•
Stone, Gary
•
Hiddessen, Amy L.
•
Dugan, Lawrence C.
•
Wu, Ligang
•
Hailey, Philip
•
Conway, James W.
•
Kuenzler, Tobias
•
Feller, Lydia
•
Cerritelli, Simona
Publication date
2009
Published in
Volume
25
Start page
1238
End page
1244
Peer reviewed
REVIEWED
EPFL units
Available on Infoscience
November 30, 2010
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