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research article
Ruthenium(II) Arene Compounds as Versatile Anticancer Agents
2009
Ruthenium-based compounds are an attractive alternative to clinically used platinum drugs due to several features including a wide range of accessible oxidation states, varied synthetic chemistry and typically lower general toxicities. One series of ruthenium(II)-arene-pta, RAPTA (pta = 1,3,5-triaza-7-phosphatricyclo[3.3.1.1] decane) compounds has been found to show particularly high selectivity towards cancer cells in both in vitro and in vivo studies.
Type
research article
Web of Science ID
WOS:000265917600011
Authors
Publication date
2009
Published in
Volume
63
Start page
217
End page
219
Peer reviewed
REVIEWED
EPFL units
Available on Infoscience
November 30, 2010
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