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research article
Retinal ischemia-induced apoptosis is associated with alteration in Bax and Bcl-x(L) expression rather than modifications in Bak and Bcl-2
Produit-Zengaffinen, Nathalie
•
Pournaras, Constantin J.
•
Schorderet, Daniel F.
2009
Purpose: Apoptosis is known to play a key role in cell death after retinal ischemia. However, little is known about the kinetics of the signaling pathways involved and their contribution to this process. The aim of this study was to determine whether changes in the expression of molecules in the mitochondrial apoptotic pathway might explain the progression of retinal damage following ischemia/reperfusion.
Type
research article
Web of Science ID
WOS:000272424100002
Authors
Produit-Zengaffinen, Nathalie
•
Pournaras, Constantin J.
•
Schorderet, Daniel F.
Publication date
2009
Published in
Volume
15
Start page
2101
End page
2110
Peer reviewed
REVIEWED
EPFL units
Available on Infoscience
November 30, 2010
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