Procédé de préparation de composés d'intérêt par cyclisation intramoléculaire et formation d'un pont éther biaryl
Novel method for intermolecular cyclization by formation of a biaryl ether bridge through the reaction as shown above. In formulas (I) and (II) R1 is a nitro radical adjacent to the oxygen bridge, Hal is a fluoride or chlorine atom, R2, R3 and R4 together form a peptidic chain, in the presence of a weak phase in a heterogeneous medium. The invention also concerns compounds of formulas (I) and (II) and the use of compounds of formula (I) to obtain useful compounds.
9460270
Alternative title(s) : (de) Verfahren zur herstellung von glycopeptid-antibiotika-vorläufern durch intramolekulare cyclisierung und erzeugung einer diarylbrücke und verfahrensmässig lergestellte verbindungen (fr) Procede de preparation de precurseurs d'antibiotiques glycopeptidiques par cyclisation intramoleculaire et formation d'un pont ether biaryl et nouveaux composes ainsi obtenus (en) Method for the preparation of glycopeptidic antibiotic precursors by intramolecular cyclisation and formation of a biaryl ether bridge and novel compounds so obtained
| Patent number | Country code | Kind code | Date issued |
JPH09508920 | JP | A | 1997-09-09 |
EP0746568 | EP | A1 | 1996-12-11 |
FR2716456 | FR | B1 | 1996-05-10 |
FR2716456 | FR | A1 | 1995-08-25 |
CA2183333 | CA | A1 | 1995-08-24 |
WO9522558 | WO | A1 | 1995-08-24 |