## Solution phase combinatorial synthesis of arylpiperazines

A solution phase combinatorial synthesis of aryl piperazines 1 and 2 is described based on the S(N)Ar reaction and Schotten-Baumann acylation. The use of excess reagent is allowed and pure arylpiperazines 1 and 2 were obtained by simple acid/base washing.

Published in:
Tetrahedron Letters, 38, 23, 4091-4094
Year:
1997
Publisher:
Elsevier
ISSN:
00404039
Laboratories: