A concise and efficient synthesis of protected actinoidic acid, the degradation product of vancomycin
Protected actinoidic acid I, one of the degrdn. products of vancomycin, has been efficiently synthesized by a convergent route which is amenable to large scale application as well as to asym. synthesis. [on SciFinder (R)]
1993
34
46
7401
4
CAN 120:164870
34-3
Amino Acids, Peptides, and Proteins
Inst. Chim. Subst. Nat.,CNRS,Gif-sur-Yvette,Fr.
Journal
written in English.
123-08-0P (4-Hydroxybenzaldehyde); 124-68-5P (2-Amino-2-methyl-1-propanol); 2973-76-4P (3-Bromo-4-hydroxy-5-methoxybenzaldehyde); 23030-39-9P (Benzene, 1-bromo-2,3,5-trimethoxy-); 36873-96-8P (2,3,5-Trimethoxybenzoic acid); 61654-67-9P (1,4-Benzenediol, 2-bromo-6-methoxy-); 119098-80-5P; 153335-56-9P; 153335-57-0P; 153335-58-1P; 153335-59-2P; 153335-60-5P; 153335-61-6P Role: SPN (Synthetic preparation), PREP (Preparation) (intermediate in prepn. of protected actinoidic acid deriv.); 58178-44-2P Role: SPN (Synthetic preparation), PREP (Preparation) (prepn. of); 121-33-5 (4-Hydroxy-3-methoxybenzaldehyde) Role: RCT (Reactant), RACT (Reactant or reagent) (reactant, in prepn. of protected actinoidic acid deriv.)
REVIEWED